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In the UK in 2012-2014, on average each year more than 4 in 10 (44%) cases were diagnosed in people aged 75 and over.Age-specific incidence rates increase sharply from around age 50-54, with the highest rates in the 85-89 age group for both males and females.UK bowel cancer incidence rates are estimated to be the 20th highest in males in Europe, and 17th highest in females. These data are broadly in line with Europe-specific data available elsewhere. Bowel cancer (C18-C21) is the third most common cancer worldwide, with more than 1,360,000 new cases diagnosed in 2012 (10% of the total).Bowel cancer incidence rates are highest in Australia/New Zealand and lowest in Western Africa, but this partly reflects varying data quality worldwide. Variation between countries may reflect different prevalence of risk factors, use of screening, and diagnostic methods.Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.rates for White males with bowel cancer range from 54.1 to 55.3 per 100,000.
For females there is a similar pattern - the age-standardised rates for White females range from 34.0 to 34.8 per 100,000, and rates for Asian and Black females are also significantly lower ranging from 11.3 to 17.5 per 100,000 and 20.4 to 31.6 per 100,000 respectively. Ranges are given because of the analysis methodology used to account for missing and unknown data.
Bowel cancer is the fourth most common cancer in the UK (2014), accounting for 11% of all new cases.
It is the third most common cancer in both males (12% of the male total) and females (10%) separately.[1-4] In 2014, there were 41,265 new cases of bowel cancer in the UK: 22,844 (55%) in males and 18,421 (45%) in females, giving a male:female ratio of .[1-4] The (AS rates) are significantly lower in England compared with Wales, Scotland and Northern Ireland for males.[1-4] Rates for females are similar across all the constituent countries of the UK.[1-4] Bowel Cancer (C18-C20), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2014 For bowel cancer, like most cancer types, differences between countries largely reflect risk factor prevalence in years past.
The introduction of the bowel screening programmes in the mid-2000s probably also plays a part. A high proportion (87-90%) of bowel cancer cases in England, Scotland and Northern Ireland have stage at diagnosis recorded.[1-3] More bowel cancer patients with a known stage are diagnosed at a late stage (52-56% are diagnosed at stage III or IV), than an early stage (44-48% are diagnosed at stage I or II).
Around 23-26% of bowel cancer patients have metastases at diagnosis (stage IV).[1-3] The stage distribution for each cancer type will reflect many factors including how the cancer type develops, the way symptoms appear, public awareness of symptoms, how quickly a person goes to see their doctor and how quickly the cancer is recognised and diagnosed by a doctor.